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Shaun Gleason

Measurement Science and Systems Engineering Division, ORNL


Shaun S. Gleason is currently the Director of the Office of Institutional Planning at the Oak Ridge National Laboratory where he is responsible for ORNL’s strategic planning process and discretionary R&D investment. Previously, he was the Group Leader of the Imaging, Signals, and Machine Learning (ISML) Group at ORNL. He has 24 years of experience in applied image processing and machine learning for industrial, security, and medical imaging applications, including real-time implementations of compute-intensive algorithms (e.g. tomographic reconstruction) on parallel computing systems. He earned the B.S., M.S., and Ph.D. degrees in Electrical Engineering from the University of Tennessee, Knoxville, with a thesis research focus on x-ray computed tomography and 2D and 3D model-based medical image segmentation. In 1998 he co-founded and was the VP of a preclinical imaging company, ImTek, Inc., that successfully transferred ORNL-developed technology into the commercial research sector. After ImTek, Inc. was acquired by CTI and then merged with Siemens Medical, he became the Director of the Preclinical Research Division of Siemens Medical until 2008, when he returned to ORNL to lead the ISML group. He has authored and coauthored over 100 publications and has been issued 8 patents in the field of electrical engineering and computer vision. He is a Senior Member of the IEEE, was chair of the East TN Chapter of the IEEE Engineering in Medicine and Biology Society (2008-2013), and has been an associate editor of the SPIE Journal of Electronic Imaging since 2008.


Gleason SS, Ferrell RK, Cheriyadat A, Vatsavai R, De S, “Semantic Information Extraction from Multispectral Geospatial Imagery via a Flexible Framework,” Invited Paper, IEEE International Geoscience and Remote Sensing Symposium, 2010.

Ryan A. Kerekes, Rodrigo A. P. Martins, Denise Davis, Mahmut Karakaya, Shaun Gleason and Michael A. Dyer, “Automated Tracing of Horizontal Neuron Processes During Retinal Development”, submitted to Neurochemical Research, 2010.

Solecki DJ, Trivedi N, Govek EE, Kerekes RA, Gleason SS, and Hatten ME, “Par6α regulated Myosin II motors drive the coordinated movement of centrosome and soma during glial-guided neuronal migration,” Neuron 63(1):63-80, 2009.

S. Gleason, M. Paulus, and D. Osborne, “Principles of Micro X-ray Computed Tomography,” Molecular Imaging: Principles and Practice, Weissleder, Ross, Rehemtulla, Gambhir, eds., B. C. Decker, Inc., 2009.

Shaun Gleason, Derek Austin, Robert Mintzer, Blake Atkins, Bing Feng, Bing Bai, “A Versatile SPECT-CT System for Small Animal Imaging,” Proc. Society of Molecular Imaging Annual Meeting, #0515, Providence, RI, September 2007.

J.S. Wall, S.J. Kennel, M.J. Paulus, S. Gleason, J. Gregor, J. Baba, M. Schell, T. Richey, B. O'Nuallain, R. Donnell, P.N. Hawkins, D.T. Weiss and A. Solomon, “Quantitative high-resolution microradiographic imaging of amyloid deposits in a novel murine model of AA-amyloidosis,” Amyloid: The Journal of Protein Folding Disorders, 12, (3), 149-156, September 2005.

Weisenberger, A. G., Gleason, S. S., Goddard, J., Kross, B., Majewski, S., Meikle, S. R., Paulus, M. J., Pomper, M., Popov, V., Smith, M. F., Welch, B. L., Wojcok, R., “A Restraint-Free Small Animal SPECT Imaging System With Motion Tracking,” IEEE Trans. on Nucl. Science, vol. 52, no. 3, pp. 638-644, June 2005.

J. Price, D. Aykac, S. Gleason, K. Chourey, Y. Liu, “Quantitative Comparison of Mitotic Spindles by Confocal Image Analysis,” Journal of Biomedical Optics, vol. 10, no. 4, 044012, July/August 2005.

Hung-Yam Chan, Hamed Sari-Sarraf, Bradley I. Grinstead, Shaun S. Gleason, “Content-Based Compression of Mammograms with Customized Fractal Encoding and a Modified JPEG2000,” J. Optical Engineering, Vol. 43, Iss. 12, 2004.

S. Gleason, H. Sari-Sarraf, M. Abidi, O. Karakashian, F. Morandi, "A New Deformable Model for Analysis of X-ray CT Images in Preclinical Studies of Mice for Polycystic Kidney Disease," IEEE Trans. on Medical Imaging, vol. 21, no. 10, October 2002.

S. Gleason, R. Ferrell, T. Karnowski, K. Tobin, “Detection of semiconductor defects using a novel fractal encoding algorithm”, Design, Process Integration, and Diagnostics in IC Manufacturing, Proceedings of the SPIE Vol. 4692, March 2002.

S. Gleason, H. Sari-Sarraf, M. Paulus, D. Johnson, S. Norton, M. Abidi, “Reconstruction of Multi-Energy, X-ray Computed Tomography Images of Laboratory Mice,” IEEE Trans. on Nuclear Science, vol.46, no.4, pt.2, pp. 1081-6, Aug., 1999.

M. Paulus, H. Sari-Sarraf, S. Gleason, M. Bobrek, J. Hicks, D. Johnson, J. Behel, L. Thompson, “A new x-ray computed tomography system for labora­tory mouse imaging,” IEEE Trans. on Nuclear Science, vol. 46, no.3, pt.2, pp. 558-64, Jun. 1999.

Tobin K. W., Gleason S. S., Karnowski, T. P., Bennett, M. H., “Semiconductor Defect Data Reduction for Process Automation and Characterization,” Journal of Process and Analytical Chemistry, vol. 3, no. 3,4, Spring, 1998.

S. Gleason, K. Tobin, T. Karnowski, “Rapid Yield Learning through Optical Defect and Electrical Test Analysis,” Proc. SPIE 23rd Annual Symposium on Microlithography, February, 1998.

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